Research in practice: Substance P antagonism in chronic pruritus

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Association of hemodialysis and pruritus in chronic renal failure

Background and aim: Pruritus is a common disabling problem in patients with end stage renal disease. Several studies has recorded the relation between pruritus with hemodialysis in chronic renal failure (CRF) patients. This study was designed to evaluate the effect of hemodialysis on pruritus of patients with CRF.Materials and Methods: After recording the demographic data and the diagnosis of d...

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Substance P and intensity of pruritus in hemodialysis and peritoneal dialysis patients

BACKGROUND Uremic pruritus is a common complication in patients undergoing dialysis. The pathophysiological mechanisms of pruritus in patients with end-stage renal disease remain unknown. Neuropeptides, including substance P, are postulated to play an important role in the pathogenesis of pruritus. The aim of this study was to evaluate the role of substance P in uremic pruritus in patients on h...

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ژورنال

عنوان ژورنال: JDDG: Journal der Deutschen Dermatologischen Gesellschaft

سال: 2014

ISSN: 1610-0379

DOI: 10.1111/ddg.12364